Sergio Escudero Palomo (born 2 September 1989 in Valladolid, Castile and León) is a Spanish professional footballer who plays for FC Schalke 04 in Germany, as a left defender.

Escudero joined Real Murcia in 2007, playing his first season as a senior with the B team, in Segunda División B. On 13 June 2009 he made his debut with the first team, playing the full 90 minutes in a 2–1 home win against UD Salamanca, as the hosts had already retained their Segunda División status.

Escudero was definitely promoted to the main squad for 2009–10, being the most utilized player in his position (2,250 minutes) as Murcia was eventually relegated, after ranking in 20th position. In late March 2010 interest surfaced from La Liga giants Real Madrid, but nothing came of it.

In the 2010 summer, 20-year old Escudero signed with FC Schalke 04 in Germany, alongside compatriots José Manuel Jurado and Raúl González, for an undisclosed fee. He made his Bundesliga debut on 26 February 2011, playing 68 minutes in a 1–1 home draw against 1. FC Nuremberg.