François Affolter is a Swiss football defender currently playing for Werder Bremen in the Bundesliga, on loan from Young Boys. He made his senior debut for Young Boys at the age of 17 years old on 14 September 2008 in a 2–1 victory over AC Bellinzona, replacing Marc Schneider in the starting eleven due to suspension. Since that match, he has been a regular starter for the club in their three-man defence, alongside Saif Ghezal and Miguel Alfredo Portillo.

Before he played with the first team, he was playing with the under 18 team. He won the under 18 championship the same year. Then, he joined the first team for friendly matches in the summer of 2008 and the new BSC Young Boys trainer Vladimir Petkovic gave him his chance. Since then he played every single matches with the first team. So far, he played ten Swiss Super League matches, two Swiss Cup matches and one UEFA Cup match and never lost a match in the Swiss Super League (seven victories and three draws).

He signed his first professional contract with BSC Young Boys on November 2008. After three seasons with Young Boys, he was loaned to German club Werder Bremen.