Mirko Valdifiori is an Italian professional footballer who plays as a midfielder for SPAL.

A Cesena youth-product, he began his career with the senior side in 2004, but was sent on loan to Serie C sides Pavia and Legnano, before moving to Serie B side Empoli in 2008. With Empoli, he became the sixth most capped player in the team's history and helped the team achieve Serie A promotion in 2014. He made his debut in the Italian top division the following season, and his performances throughout the year earned him a transfer to Napoli in 2015. Following a successful first season in Serie A with Empoli, he also earned his first international call-up in 2015, making his Italy debut the same year.

A creative, right-footed central midfielder with good vision, Valdifiori's preferred role is as a deep-lying playmaker in front of the defence, where he is able to utilise his passing ability to set the tempo of his team's play, and create scoring opportunities for team-mates. Although he is not known for scoring goals, he is an accurate set-piece taker, renowned for his ball delivery from free-kicks. His style of play is inspired by Andrea Pirlo.