Simone Padoin is a versatile Italian footballer, who plays primarily as a left wingback or a midfielder, for Italian club Juventus F.C.

A product of Atalanta's fruitful youth academy, Simone joined Vicenza from Atalanta in a co-ownership deal (exchanged with Davide Brivio) which became full-ownership one year later. At the beginning of the 2007–08 season, he returned to Atalanta when the club bought back his full playing rights from Vicenza. He added three more years to his contract on May 2009, which took his deal to June 2013.

After the end of the 2009-10 Serie A season, he was borrowed by Juventus for their US tour, along with 3 other players. He played a few games for Juventus in their pre-season tour and then returned to Atalanta for their own preseason work.