Diego Antonio Reyes Rosales is a Mexican professional footballer who plays as a centre-back for Portuguese club FC Porto and the Mexico national team.

Reyes has been described as "intelligent in his positioning, comfortable in possession and strong in the air", as well as being praised for "his ability to time challenges play crisp passes and keep possession when under pressure". Though mainly a defender, Reyes has also been deployed as a defensive midfielder throughout his career.

Reyes made his professional debut with Club America in April 2010, and won his first league title in 2013. He joined FC Porto that same year, but spent a majority of his time loaned out to Spanish sides Real Sociedad and Espanyol.

At international level, Reyes has played for various national youth teams for Mexico, including the under-20 team which finished third at the 2011 FIFA U-20 World Cup. He was also a part of the under-23 squad that won the gold medal at the 2012 Summer Olympics, playing in every match. He has represented Mexico at the 2014 FIFA World Cup, as well as the 2013 and 2017 FIFA Confederations Cup.